Situated in the iSimangaliso Wetland Park, which forms part of a World Heritage Site, Mkhuze Game Reserve is one of the countries top birding sites with well in excess of 450 species having been recorded. The varied habitats also provide for a wide diversity of mammal species including four of the Big Five. This ensures numerous photographic opportunities.
Accommodation ranges from camping and caravanning through to hutted and tented accommodation at Mantuma camp. The Nhlonhlela Bush Lodge is an eight bed lodge that overlooks the fever tree lined Nhlonhlela Pan. There are six game viewing hides scattered within the reserve. Guided walks and night drives may be booked through the reception office. There is a small shop and petrol is also available. Swimming pools are available in both the campsite and at Mantuma camp.